Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKBKB All Species: 20.91
Human Site: T693 Identified Species: 46
UniProt: O14920 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14920 NP_001547.1 756 86564 T693 Q L M S Q P S T A S N S L P E
Chimpanzee Pan troglodytes XP_528121 757 86974 T694 Q L M S Q P S T A S N S L P E
Rhesus Macaque Macaca mulatta XP_001096913 756 86591 T693 Q L M S Q P S T A S N S L P E
Dog Lupus familis XP_539954 755 86445 P693 Q L L A Q P S P A P S S L P E
Cat Felis silvestris
Mouse Mus musculus O88351 757 86672 S693 Q L M S Q P S S A C D S L P E
Rat Rattus norvegicus Q9QY78 757 86848 S693 H L M S Q P S S A C D S L P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509921 757 87360 A693 Q L L S Q P P A V P C S L P E
Chicken Gallus gallus Q5ZJB4 759 86125 A694 G T A S T P A A T W V P Q S S
Frog Xenopus laevis Q6GM53 743 85134 S678 T P I T S R T S A W S D Q S S
Zebra Danio Brachydanio rerio Q4G3H4 758 87129 S694 Q T Q A Q C S S R L P M S L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEZ5 751 86354 L688 K E I F Q I N L Q M L M S A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 99.7 94.9 N.A. 91.8 91.2 N.A. 88.5 49.2 50.4 51.5 N.A. 25 N.A. N.A. N.A.
Protein Similarity: 100 98.4 99.7 97 N.A. 95.5 95.3 N.A. 92.7 67.8 68.3 67.9 N.A. 42.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 80 66.6 N.A. 60 13.3 6.6 20 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 86.6 N.A. 66.6 20 40 40 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 0 0 10 19 64 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 19 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 19 10 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 55 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 64 19 0 0 0 0 10 0 10 10 0 64 10 0 % L
% Met: 0 0 46 0 0 0 0 0 0 10 0 19 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 28 0 0 0 0 % N
% Pro: 0 10 0 0 0 73 10 10 0 19 10 10 0 64 0 % P
% Gln: 64 0 10 0 82 0 0 0 10 0 0 0 19 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 64 10 0 64 37 0 28 19 64 19 19 28 % S
% Thr: 10 19 0 10 10 0 10 28 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _